The Stenting in the Treatment of Aneurysm Trial

OBJECTIVES	To establish a research context for using stent-assisted coiling in treating unruptured intracranial aneurysms by comparing coiling alone versus the use of a self-expandable stent in addition to coiling.
STUDY	Investigator-led, parallel, multicenter, randomized controlled (1:1) clinical trial conducted in 4 university hospitals in Canada and France from 2011 and 2021.
POPULATION	Patients >18 years of age with a life expectancy of at least two years with at least one unruptured intracranial aneurysm prone to recurrence defined as a large (≥10 mm) aneurysm (STAT-1), a recurrent aneurysm after previous coiling (STAT-2), or a wide neck (≥4 mm) aneurysm of <10 mm (STAT-3).
ENDPOINTS	The primary outcome was a composite of treatment failure (angiographic recurrence of the lesion) and treatment- or aneurysm-related death or dependency precluding follow-up angiography. Secondary outcomes included mRS score at discharge and 12 months post-treatment, success occluding the aneurysm at the end of the procedure, and perioperative complications (ischemic strokes and intracranial hemorrhages within 31 days of the intervention), among others.

The Stenting in the Treatment of Aneurysm Trial - STAT