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Trial of Thrombectomy 6 to 24 Hours after Stroke Due to Basilar Artery Occlusion. BAOCHE (Basilar Artery Occlusion Chinese Endovascular trial)

Last update on June 5, 2023
OBJECTIVES To assess the effect and safety of endovascular thrombectomy in conjunction with medical therapy, as compared with medical therapy alone, in patients with acute ischemic stroke due to basilar artery occlusion and an absence of a large baseline infarct on neuroimaging who underwent randomization 6 to 24 hours after symptom onset.
STUDY Investigator-initiated, multicenter, open-label, randomized, controlled trial with blinded outcome evaluation.
POPULATION Patients from 18-80 years of age with basilar artery occlusion or intracranial segments of both vertebral arteries that could be treated within 6 to 24 hours after symptom onset, pre-stroke score of 0-1 on the modified Rankin Scale, Initial NIHSS: ≥ 10, later modified to ≥ 6 to allow higher enrollment.
ENDPOINTS An original primary outcome of a score of 0 to 4 on the modified Rankin Scale was later changed to a modified Rankin Scale score of 0 to 3 (good functional status).

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Come and join us across the globe
 Founded by Pr. Jacques Moret