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Sequential asymptomatic intracranial atherosclerosis (ICAD) - to be treated, or not

Last update on November 28, 2022

Find out how Dr Jain Chirag treated sequential asymptomatic intracranial atherosclerosis (ICAD) - or not.

Case presentation
  • 57-year-old male patient
  • Recurrent ischemic CVA
  • Right hemiparesis
  • 3 episodes in 3 months
  • Gradual recovery
  • On antiplatelets – Eco 150 mg, Clop 75 mg & statins

 

Sequential asymptomatic intracranial atherosclerosis (ICAD)
Sequential asymptomatic intracranial atherosclerosis (ICAD)

 

  • Accumulation of disease burden
  • Memory loss, depression
  • mRS 3 now

 

Sequential asymptomatic intracranial atherosclerosis (ICAD)

 

Sequential asymptomatic intracranial atherosclerosis (ICAD)

 

Sequential asymptomatic intracranial atherosclerosis (ICAD)

 

Sequential asymptomatic intracranial atherosclerosis (ICAD)

 

Sequential asymptomatic intracranial atherosclerosis (ICAD)
Treatment options
  • Best medical management (eco 300 clop 150 high statins, exercise) & wait for stroke
  • Active intervention - two sessions / both at the same time - distal first or proximal first
Sequential asymptomatic intracranial atherosclerosis (ICAD)

R EJV -> Facial vein navigation

Tunnelling for Gold (through an occluded SOV in CCF)

In use: 014” exchange length microwire / In use: coronary balloon 2.25 x 10 RX SC

Sequential asymptomatic intracranial atherosclerosis (ICAD)

In use : coronary balloon 2.25 x 10 RX, SC 

Sequential asymptomatic intracranial atherosclerosis (ICAD)

In use : coronary DES RX (Zotarolimus) 4 x 8 mm

Sequential asymptomatic intracranial atherosclerosis (ICAD)

In use: coronary balloon 2.25 x 10 RX, SC 

Sequential asymptomatic intracranial atherosclerosis (ICAD)
Conclusion
  • Now on BMM,
  • No recurrence
  • Improvement in memory loss and neuropsychiatric symptoms

Key address

  • Sequential ICAD – proximal or distal first?
  • Asymptomatic critical ICAD / precious artery – beyond guidelines
  • ICAD treatment for neuropsychiatric symptoms, depression and memory loss
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