The CHOICE-2 trial - Adjunctive intra-arterial alteplase after successful thrombectomy for acute ischemic stroke

In this discussion, Nanthiya Sujijantarat sits down with Mario Martínez-Galdámez to break down the highly anticipated CHOICE-2 Randomized Controlled Trial, freshly published in JAMA (May 2026).

While mechanical thrombectomy achieves excellent large vessel reopening, clinical recovery doesn't always follow. Why? Because angiographic reperfusion does not always equal microvascular tissue perfusion.

Discover how the intra-arterial delivery of Alteplase after thrombectomy is changing the game and watch until the end to get the exact patient selection criteria and technical protocols used in this practice-changing trial.