Lymphatic malformation of the tongue - Bleomycin sclerotherapy

• 5-year-old male patient, diagnosed case of mixed lymphovascular malformation of the tongue and submandibular area, De Serres stage V
• Tongue mass since birth, with episodes of sudden increase followed by spontaneous regression, as claimed by parents.
• A few months prior to consultation, noted enlarging and friable tongue mass, with fever and loss of appetite. Consulted a private physician, and was referred to CLMMRH.
• CT scan showed a large, mildly enhancing, cystic mass in the suprahyoid neck extending into the sublingual space (floor of the mouth). Tiny calcification seen in right aspect of mass. Ultrasound showed a spongiform focus in the submandibular area.
• A multidisciplinary conference was organized, and we were given 3 sessions to make the malformation shrink.
• Computed lifetime dose of Bleomycin given the patient's weight (15 kg) at presentation was 60 U, computed at 4 mg/kg

On consultation

After 3 sessions of Bleomycin sclerotherapy