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Watch Peter Mitchell discussing the results of "Tenecteplase versus Alteplase before Thrombectomy for Ischemic Stroke" a study published in April 2018 in the New England Journal of Medicine, which demonstrated that Tenecteplase before thrombectomy was associated with a higher incidence of reperfusion and better functional outcome than alteplase among patients with ischemic stroke treated within 4.5 hours after symptom onset.