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mohd shafie abdullah – April 26, 2013
“I'm thinking of deploying telescoping approach of 2 Leos and jailing technique with loose packing...”
Pakrit Jittapiromsak – April 16, 2013
“Thank you for your comment. Honestly, in my experience, if the stent(s) is(are) placed and oppose...”
Steve Dechan – April 13, 2013
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wael elshawaf – April 13, 2013
“Weal EL-shawaf ,MD. Thank you for all Pr Dr how start this decision and to learn more and more ,s...”
Willem Jan van Rooij – April 5, 2013
“I am surprised by the comment of Laurent Spelle. The only thing we can learn from a case like thi...”
Cerecyte Coil Trial: Procedural Safety and Clinical Outcomes in Patients with Ruptured and Unruptured Intracranial Aneurysms
American Journal of Neuroradiology by
- Authors: Coley S, Sneade M, Clarke A, Mehta Z, Kallmes D, Cekirge S, Saatci I, Roy D, Molyneux A.
- Reference: AJNR Am J Neuroradiol. 2012 Mar;33(3):474-80.
- Published: March 2012
- Link: Access the abstract here
Cerecyte Coil Trial (CCT) is a prospective randomized controlled trial comparing polyglycolic acid loaded Cerecyte coils with bare platinum coils in treatment of aneurysms: ruptured and unruptured situation. This trial included 500 patients from 23 centers in North America, Europe, and Japan. Authors reported their secondary aims regarding clinical outcomes and adverse events up to 6-month follow-up in this publication. The primary aim regarding angiographic occlusion will be reported separately. Cerecyte arm showed a bit inferior to bare platinum arm in outcomes of ruptured cases at discharge and outcomes of unruptured cases at 6-month follow-up. No difference in adverse events was found. Overall, due to small amount of patients with poor clinical outcome in this study with minor outcome differences between groups, Cerecyte coils seem to be safe for clinical usage. Angiographic outcome is the most interesting piece of data to decide its usefulness.